A class of medications used to treat cluster and migraine headaches. Members of this class act as agonists at 5-hydroxytryptamine (5-HT) receptors in the brain. Each of them has a generic name that ends in “-triptan,” including frovatriptan, naratriptan, rizatriptan, and sumatriptan.
A category of medications that attach to serotonin receptors and imitate the effects of serotonin. It is believed that these drugs aid in the treatment of migraine headaches by narrowing blood vessels in the cranium, impeding inflammatory neuropeptides, and interrupting the transmission of pain signals.