Tibolone is a medication utilized for short-term relief of menopausal symptoms and also offers some protection against osteoporosis, although it’s generally not the first choice for treating this condition. Administered continuously, the drug mimics the effects of both estrogen and progestogen. Potential side effects may include irregular vaginal bleeding, weight fluctuations, ankle swelling due to fluid retention, dizziness, skin reactions, headaches, and the growth of facial hair.