A rare disorder present from birth, severe combined immunodeficiency (SCID) results in a poorly functioning or non-existent immune system. Infants born with this condition are extremely vulnerable to infections. They may exhibit poor growth and suffer from multiple severe infections, including those affecting the respiratory and gastrointestinal systems, as well as skin rashes, recurring oral thrush, and pneumonia.
Prompt diagnosis of SCID is crucial and is usually confirmed through blood tests that measure lymphocyte levels, a specific kind of white blood cell. The most promising treatment for a cure is a bone marrow transplant, ideally conducted within the first few months of life. Many children who receive timely treatment for SCID go on to live normal, healthy lives.