Sequestration

The process whereby necrotic bone separates from native healthy bone and forms a sequestrum.


The act of putting someone in an isolated place.


The loss of blood into spaces in the body, reducing the circulating volume. It can occur naturally or can be produced artificially by applying tourniquets.


The formation of a sequestrum.


The formation of a fragment or fragments of dead bone, which have lost their blood supply and become detached from adjoining sound bone.


The formation of a fragment of dead bone and its separation from the surrounding tissue.


The spleen performs a process wherein it selectively removes blood cells from circulation and retains them within its storage.


The detachment of a sequestrum, or a fragment of dead bone, from the surrounding healthy bone is referred to as sequestration. The term also applies to the trapping of blood or other fluids in bodily compartments, leading to their removal from active circulation and resulting in low blood pressure. In the context of sickle cell anemia, sequestration crises can occur when blood accumulates in the spleen and liver.


 


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