Schilder disease is a very serious progressive disorder characterized by the breakdown or loss of the myelin sheath surrounding nerve cells in the brain and nervous system in addition to the dysfunction of the adrenal gland. There are three forms of this rare genetic disorder: childhood adrenoleukodystrophy (ALD) in 35% of cases, adrenomyeloneuropathy (AMN) occurring in adolescent males and adult men in 40-45% of cases, and Addison’s disease in 10% of cases.
A rare demyelinating disease of the central nervous system (a variant of multiple sclerosis). It results in brain lesions that may resemble tumors or abscesses during neuroimaging. The disease may respond to treatment with immunosuppressing drugs.
A degenerative condition affecting the brain’s nerve cells, leading to a gradual decline in cerebral function. Commonly, it begins with vision loss not attributed to eye ailments, subsequently followed by hearing loss, muscle incoordination, spastic paralysis, and eventually severe cognitive impairment. The exact origin of this disease remains unidentified, and no treatment has been proven to alter its progression.