Nephropathy caused by the use of radiological contrast media (e.g., the “dye” used during angiography). It is usually defined as one of the following: an increase in the serum creatinine of 0.5 mg/dL within 48 hr of exposure to contrast agents when no other cause is apparent; a decrease in renal function of 25%; or any deterioration in renal function that results in clinically significant adverse effects on a patient’s health.