The proenzyme of plasmin, whose primary role is the degradation of fibrin in the vasculature.
Precursor of fibrinolysin (plasmin). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.
Inactive protein precursor to plasmin; found in many tissues and body fluids; prevents formation of abnormal blood clots as well as functions in the lysis (breakdown) of normally formed clots.
Drugs that dissolve already-formed blood clots by converting plasminogen to an enzyme that breaks the fibrin strands.
A test done on blood to determine adequacy of the blood clotting process, and to diagnose blood clotting disorders in newborn infants.
A substance normally present in the blood plasma that may be activated to form plasmin.
A precursor of plasmin, an enzyme that digests the protein fibrin the main constituent of blood clots. When tissue is damaged, activators are released which provoke the conversion of plasminogen into plasmin.
A protein found in many tissues and body fluids; important in preventing fibrin clot formation.