A presenile degenerative disease of the brain, possibly hereditary, that affects the cerebral cortex focally, particularly the frontal lobes. Symptoms include intellectual deterioration, emotional instability, and loss of social adjustment.
A form of presenile dementia.
A rare form of presenile dementia, in which a disorder of the lipoid metabolism causes mental impairment, anaemia, loss of weight and swelling of the spleen and liver.
Form of presenile dementia occurring in middle-aged people, characterized by degeneration in the frontal and temporal lobes of the brain (not diffuse throughout the brain as in Alzheimer’s disease) and manifested by changes in behavior and deterioration of intellectual abilities.
A type of irreversible dementia in older people characterized by frontal lobe degeneration in the brain and the presence of distinctive Pick cells in brain tissue. Symptoms include impaired speech, inability to name objects, loss of insight, apathy, impulsiveness, dietary changes, and lack of inhibitions. As in Alzheimer’s disease, over time people who have Pick disease grow unable to perform the usual activities of daily living and eventually become incapacitated.
Coloration of the skin, hair, and eyes with the pigment melanin. Pigmentation can be affected by many factors, including heredity, hormones, injury, and exposure to heat or radiation. Skin conditions characterized by altered pigmentation include freckles, melasma, pityriasis alba, suntans, tinea versicolor, and vitiligo. In most cases, the skin changes are cosmetic and do not affect general health. Treatments for severe pigment disorders include bleaching creams, topical corticosteroids, and phototherapy (treatment with light).
A rare cause of dementia in middle-aged people. The damage is mainly in the frontal and temporal lobes of the brain, in contrast with the diffuse degeneration of Alzheimer’s disease.
A rare type of primary major neurocognitive disorder that affects the frontal lobes of the brain. It is characterized by a progressive loss of social skills, language, and memory, leading to personality changes and sometimes loss of moral judgment.
A complex disease characterized by inflammation of one or more internal membranes. In some cases, it is caused by tuberculosis. When this condition affects multiple membranes simultaneously, it’s referred to as Concato’s disease or polyserositis. When it predominantly impacts the pericardium, it’s known as Pick’s disease or chronic constrictive pericarditis, or pericardiac pseudo-cirrhosis of the liver. However, the latter condition is typically of tuberculous origin. The inflammation of the pericardium disrupts heart function, leading to vein congestion extending to the liver, which becomes affected as well. This disease follows a prolonged, chronic course with a gradual increase in venous congestion, resulting in more pronounced interference with both heart function and liver performance. Treatment involves surgically removing the pericardium and addressing any concurrent tuberculosis infection, if present.