A dopamine agonist used as an adjunctive treatment with carbidopa-levodopa therapy in the management of signs and symptoms of parkinson’s disease. Pergolide (including all generic and brand [permax] products) was withdrawn from the u.s. Market in 2007 after several published studies revealed a link between the drug and increased rates of valvular dysfunction.
An antidyskinetic drug; an ergot alkaloid used to treat Parkinson disease. In combination with levodopa or with the levodopa-carbidopa combination, pergolide (Celance, Permax) works by stimulating the specific parts of the central nervous system that are involved in Parkinson disease.
This medication is employed to manage parkinsonism, a neurological condition arising due to dopamine deficiency. It operates by activating dopamine receptors within the brain.