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Is an inflammation of the pleura, the lining of the pleural cavity surrounding the lungs, which can cause painful respiration and other symptoms. Also known as pleuritis. Inflammation of the serous membrane investing the lungs and lining the walls of the thoracic cavity. Inflammation of the pleura membrane enveloping the lung. Inflammation of the membranes…

Phospholipase C gamma plays a central role in signal transduction.  

Is an acetylated derivative of glycerophosphorylcholine, released by basophils and mast cells in immediate hypersensitive reactions and macrophages and neutrophils in other inflammatory reactions. One of its main effects is to induce platelet aggregation.  

The proenzyme of plasmin, whose primary role is the degradation of fibrin in the vasculature. Precursor of fibrinolysin (plasmin). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic…

A proteinase enzyme that is responsible for digesting fibrin in blood clots. A product of the lysis of plasminogen (profibrinolysin) by plasminogen activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis…

A serine protease, synthesized in the liver and circulates in the plasma.  

The yellow-colored liquid component of blood, in which blood cells are suspended. The clear, yellowish, fluid part of the blood that carries the blood cells. The proteins that form blood clots are in plasma. A pale, amber-colored fluid constituting the fluid portion of the blood in which are suspended the cellular elements. Plasma contains 8-9…

A platelike epithelial thickening in the embryo where some organ or structure later develops. Any of the thickened areas of ectoderm in the embryo that will develop into nerve ganglia or the special sensory structures of the eye, ear, or nose. In embryology, a plate like thickening of epithelium, usually the ectoderm, that serves as…

Protein Kinase C delta inhibitors that induce apoptosis of haematopoietic cell lines.  

Protein kinase C, a membrane bound enzyme that phosphorylates different intracellular proteins and raised intracellular Ca levels.