Mindblown: a blog about philosophy.
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Immunoadhesin
A genetically engineered, antibody like protein that fuses the Fc region of an immunoglobulin and the ligand-binding region of a receptor or adhesion molecule. Immunoadhesins can be used to direct the immune-responsive effect of cytokines to tumor cells and to stimulate the destruction of such cells.
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Waning immunity
The progressive loss of protective antibodies against an antigen or disease that occurs with the passage of time. It is a crucial factor in vaccination.
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Local immunity
Immunity limited to a given area or tissue of the body.
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Congenital immunity
Immunity present at birth. It may be natural or acquired, the latter depending on antibodies received from the mother’s blood.
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Immune-mediated inflammatory reaction
The process by which the immune system destroys, dilutes, or walls off injurious agents and injured tissue. Small blood vessels dilate and become permeable. This increases blood flow and permits exudation of plasma and leukocytes. The cells arriving from the blood include monocytes, neutrophils, basophils, and lymphocytes; those of local origin include endothelial cells, mast…
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Varicella zoster immune globulin
An immune globulin used for passive immunization of susceptible immunodeficient individuals after significant exposure to varicella. VZIG does not modify established varicella-zoster infections. An immune globulin obtained from the blood of healthy persons found to have high antibody titers to varicella-zoster. A compound with the potential to alleviate the intensity of symptoms associated with chickenpox.…
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Intravenous immune globulin
An immune globulin preparation used intravenously in patients with immunodeficiency syndromes and in immunosuppressed recipients of bone marrow transplants. In conjunction with aspirin, it is the standard of care for children during the first 10 days of Kawasaki disease to prevent the development of coronary aneurysms.
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Intramuscular immune globulin
A preparation of immune globulin that is injected directly into a muscle. It can be used to provide passive immunity to a wide variety of infections including, for example, hepatitis A.
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Cytomegalovirus immune globulin intravenous
An immune globulin preparation containing cytomegalovirus (CMV)- specific antibodies used to treat or prevent CMV infection after organ or tissue transplantation. Antiviral drugs like ganciclovir may be used for the same purpose.
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Immune reconstitution
The restoration of normal or improved immune function in a person with congenital or acquired immunodeficiency syndrome. Bone marrow transplantation or drug therapies may be used, depending on the underlying cause of the immune failure.
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