Opioid receptors

A group of G-protein coupled receptors located in the brain and various organs that bind opiates or opioid substances.


Receptors located in the brain and spinal cord, as well the intestinal tract, that bind with endogenous opioids (endorphins) and opiate drugs. There are four major opioid receptor types—mu (μ), delta (δ), kappa (κ) and nociceptin (ORL-1)—and numerous subtypes (e.g., μ1, μ2, μ3). The opioid system is known primarily for its role in pain modulation, but it may have other functions as well.


Structures on the surface of neuronal cells that mediate the function of opiates. Both naturally produced opiates (endorphins) and drugs are bound by these receptors and when bound analgesia is produced.


Chemical particles in cells to which opioids and opiates attach.


Within the intricate network of the human anatomy, there exist specialized receptors strategically positioned in the brain as well as diverse organs. These receptors possess the remarkable ability to form connections with opiate or opioid substances, thereby facilitating their binding process. This extraordinary interaction between receptors and these specific substances plays a pivotal role in numerous physiological processes, contributing to the intricate functioning of the human body.


 


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