A group of antidepressant medications that exert their antidepressant and anxiolytic effects through inhibition of the enzyme monoamine oxidase (MAO) in the brain, resulting in elevated levels of neurotransmitters. Maois are infrequently prescribed because of the risk of hypertensive crisis if dietary restrictions are not followed and because of the potential for dangerous drug-drug interactions.
A group of antidepressant drugs that inhibit the enzyme mono- amine oxidase in the brain and raise the levels of biogenic amines.
Inhibitor of monoamine oxidase that degrades the neurotransmitters adrenaline, noradrenaline, dopamine and serotonin.
One member of a group of drugs that can be used to treat depression.
A group of antidepressant drugs that prevents the enzyme monoamine oxidase from deactivating neurotransmitters in the central nervous system with the resultant increase in norepinephrine and serotonin available in the synapse, the mood is elevated.
A drug which inhibits monoamine oxidase and is used to treat depression, e.g. phenelzine. Its use is limited, because of the potential for drug and dietary interactions and the necessity for slow withdrawal. It can also cause high blood pressure.
Group of medications used to treat depression. Consumption with tyramine-containing foods can cause severe hypertension.
Antidepressant drugs. Monoamine oxidase inhibitors, also called MAOIs, relieve depression by blocking the action of a chemical substance in the nervous system called monoamine oxidase. There are currently only three MAOIs available orally for prescription in the United States: iso-carboxazid, phenelzine, and tranylcypromine.
One member of a group of drugs that can be used to treat depression and Parkinson’s disease. Nonselective versions of these medications produced hypertensive crises and other severe side effects when they were taken with tyramine-containing foods (some cheeses) and several other drugs. Newer members of this class of drugs do not have these effects, but should be used with caution, especially in persons who take selective serotonin reuptake inhibitors.
An older class of antidepressants believed to increase the brain’s serotonin, norepinephrine, and dopamine levels.
A collection of pharmaceuticals classified as antidepressant medications.
Commonly recognized as MAOIs, monoamine oxidase inhibitors constitute one of the three primary categories of antidepressant medications. Their mechanism involves hindering the enzymatic breakdown of specific neurotransmitters by monoamine oxidase. The resultant elevation in neurotransmitter levels is linked to enhanced mood.
Frequent medications in this category encompass phenelzine and isocarboxazid. All MAOIs have interactions with specific medications and foods, like cheese and red wine. However, moclobemide is a reversible MAOI, known as a RIMA, which reduces the likelihood of adverse reactions.