Linkage

The tendency of two or more genes in the same chromosome to remain together from one generation to the next more frequently than expected according to the law of independent assortment.


A phenomenon discovered by Thomas Hunt Morgan in the early 1900s via his experiments with fruit flies. This term describes the tendency of genes to be inherited together as a result of their locations being physically close to each other on the same chromosome; measured by percent recombination between loci. Because the locus (i.e., location of gene on the chromosome) determines the likelihood that two genes will go together into offspring, “marker genes” that are linked to a gene (e.g., for a given trait or disease) of interest can be utilized to predict the presence of that (trait or disease-causing) gene.


In genetics, the inheritance of traits in groups because their genes are in the same chromosome.


(Of genes) the fact of being close together on a chromosome, and therefore likely to be inherited together.


The situation in which two or more genes lie close to each other on a chromosome and are therefore very likely to be inherited together. The further two genes are apart the more likely they are to be separated by crossing over during meiosis and to come to lie on different homologous chromosomes.


A description that in genetics means circumstances in which two or more genes lie near each other on a chromosome and so may well be inherited together.


In genetics, the association between distinct genes that occupy closely situated loci on the same chromosome. This results in an association in the inheritance of these genes.


 


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