The formation of a phosphodiester bond to link two adjacent bases separated by a nick in one strand of a double helix of DNA (deoxyribonucleic acid). The term can also be applied to blunt-end ligation and to the joining of RNA (ribonucleic acid) strands.
Process of tying off blood vessels or constricting other body tissues for therapeutic purposes.
Surgical operation to tie up a blood vessel.
The enzyme-catalyzed reaction that results in the joining of two substrates.
Tying a blood vessel or duct with silk thread, wire, or other filament to prevent bleeding (e.g., during surgery) or to prevent passage of material through a duct (e.g., to prevent fertilization from occurring in the fallopian tube).
Tying up or binding of a blood vessel or duct to prevent bleeding of another structure. Ligature is the threadlike material used in ligation to tie off the blood vessel or duct.
Ligation is a surgical procedure involving the use of a ligature, which is a thread-like material, to secure and close off a duct or a blood vessel. This method is employed to halt bleeding from blood vessels or to seal off a duct or tubal structure within the body. The term is notably used in the context of tubal ligation, a sterilization technique that involves tying off the fallopian tubes.