Lactate dehydrogenase (LDH)

Enzyme that catalyzes the conversion of lactate to pyruvate.


An enzyme that catalyzes the oxidation of lactate. It is found in a variety of tissues (lung, kidney, heart, liver, blood) in slightly different forms called isoenzymes. Detection of these isoenzymes in the bloodstream is used in the diagnosis and management of a variety of illnesses.


An enzyme with the potential to serve as a discerning indicator within the bloodstream for certain types of malignancies.


An enzyme that facilitates the conversion of pyruvate to lactate, a process that is the final step in glycolysis. Conversely, it also catalyzes the initial step in the burning of lactate in the heart or its transformation into glucose in the liver. This enzyme is present in the cytoplasm of almost all cells, and its occurrence in serum is utilized for clinical diagnosis.


 


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