A disorder that occurs in males at puberty where the hypothalamus fails to signal for the release of male hormone, thus preventing the development of adult secondary sex characteristics.
A disorder where patients have anosmia (loss of the sense of smell) and hypogonadism.
A disorder whose hallmarks are congenital absence of the sense of smell and decreased functional activity of the sex organs, resulting from insufficient production of gonadotropin releasing hormone. Affected individuals also may have hearing loss and other deficits caused by intracranial, sinus, or facial abnormalities.
An inherent disorder marked by an insufficiency of gonadotropin-releasing hormone (GnRH), a hormone generated in the hypothalamus. This hormone plays a pivotal role in controlling the secretion of other hormones within the pituitary gland, which subsequently activate the testes. The scarcity of GnRH causes a delay or occasional obstruction in typical sexual maturation during puberty. This syndrome is additionally linked to colorblindness and anosmia (loss of sense of smell). Treatment for Kallmann’s syndrome involves hormone replacement therapy to substitute GnRH.