A skin disease that may be present at birth or develop in the first months of life. Firm dome-shaped yellow, pink, or orange papules, ranging from a few millimeters to 4 cm in diameter, are usually present on the scalp, face, and upper trunk. Biopsy of these lesions reveals lipid-filled histiocytes, inflammatory cells, and Touton giant cells (multinucleated vacuolated cells with a wreath of nuclei and peripheral rim of foamy cytoplasm). The lesions regress spontaneously during the first years of life. Juvenile xanthogranuloma of the iris is one of the most common causes of bleeding into the anterior chamber of the eye in childhood.