Disease characterized by enlargement of the lymph glands, spleen and anemia.
A cancer of lymph cells that originates in one lymph node and later spreads to other organs.
A lymphoma. Occurs mainly in people between 20 and 45 years. It is characterized by painless swelling of the lymph glands located in the neck, armpits, and groin. The cause is unclear; however, biopsy indicates malignancy of the reticular cells and the Reed-Stemberg cells.
A malignant disease in which the lymph glands are enlarged and there is an increase in the lymphoid tissues in the liver, spleen and bone marrow. It is frequently fatal if not treated early.
Malignant lymphoma with characteristic large multinucleated cells, occurring in a single lymph node of the neck, axilla, or groin, spreading to adjacent nodes and tissues if left untreated.
A cancerous disease of the lymph glands, spleen, liver, bone marrow, and certain other tissues. Fever, sweating, weakness, weight loss, and anemia are among the principal symptoms.
A type of lymphoma; cancer of the lymphatic tissue. Hodgkin disease is an uncommon lymphoma, accounting for less than 1 percent of all cases of cancer in the United States. All other lymphomas are called non- Hodgkin lymphomas. Hodgkin disease is commonly characterized by painless enlarged lymph nodes in the neck, underarm, or groin; weight loss; recurrent fevers; night sweats; and anemia. There are no benign forms of the disease. Because Hodgkin disease develops in lymphatic tissue, which is present throughout the body, it spreads easily and progressively from one group of lymph nodes to the next. Eventually, it can spread to almost every part of the body. Diagnosis depends on a biopsy of part or all of a lymph node.
A malignant disease of lymphatic tissues, usually characterized by painless enlargement of one or more groups of lymph nodes in the neck, armpits, groin, chest, or abdomen; the spleen, liver, bone marrow, and bones may also be involved. Apart from the enlarging glands, there may also be weight loss, fever, profuse sweating at night, and itching (known as B symptoms). Treatment depends on the extent of disease and may include surgery, radiotherapy, drug therapy, or a combination of these. Drugs used in the treatment of the disease include nitrogen mustard, vincristine, procarbazine, prednisone, chlorambucil, and vinblastine. Many patients can be cured; in the early stages of the disease this may be in the order of 85% or more.
A malignant lymphoma whose pathological hallmark is the Reed-Stemberg cell, a giant, multinucleated cell, usually a transformed B lymphocyte. The disease may affect persons of any age but occurs most often in adults in their early 30s. The incidence of the disease is higher in males than in females. It is slightly more common in Caucasians than in other racial groups. The disease has a bimodal age distribution; it is common in people between the ages of 15 and 35, and in another group of patients older than 50. About 7500 new cases of the disease are diagnosed annually in the U.S. This lymphoma typically begins in a single lymph node (esp. in the neck, axilla, groin, or near the aorta) and spreads to adjacent nodes if it is not recognized. It may metastasize gradually to lymphatic tissue on both sides of the diaphragm or disseminate widely to tissues outside the lymph nodes. The degree of metastasis defines the stage of the disease; early disease (stage I or II) is present in one or a few lymph nodes, whereas widespread disease has disseminated to both sides of the diaphragm (stage III) or throughout the body (stage IV). The lower the stage of the disease, the better the prognosis. Patients with stage I Hodgkin’s lymphoma have a 90% survival 5 years after diagnosis.
Cancer is a malignant condition that primarily originates in the lymph nodes and has the potential to spread and impact other organs beyond the lymphatic system as it advances.
Hodgkin’s disease is a relatively rare malignant condition characterized by an overgrowth of cells in lymphoid tissue, primarily located in the lymph nodes and spleen. Also referred to as lymphoma, this disease tends to affect men more than women. The cause remains unidentified.
The primary symptom often noticed is the non-painful swelling of lymph nodes, particularly in the neck or underarm area. Individuals may also experience a general sense of being unwell, accompanied by fever, loss of weight, and perspiration during the night. Itchiness all over the body may occur, and infrequently, there could be pain in the enlarged lymph nodes following the consumption of alcohol. As the illness advances, there is a corresponding decline in the functioning of the immune system.
A Hodgkin’s disease diagnosis is typically confirmed through a biopsy, which involves extracting a small tissue sample from a swollen lymph node for detailed microscopic examination. The detection of specific cells known as Reed-Sternberg cells in the biopsy sample verifies the diagnosis. The stage of the disease, or its severity, can be evaluated using chest X-rays, CT scans, or abdominal MRI and a bone marrow biopsy. The disease can generally be effectively treated and potentially cured through radiotherapy, chemotherapy, or a combined approach of these two treatments.
A condition primarily affecting the lymph nodes, causing them to enlarge and take on a rubbery texture. The enlargement typically does not cause pain. It usually starts in one group of lymph nodes and then spreads to other groups, as well as to the lymphoid tissue in organs like the spleen and liver, which also become enlarged. Symptoms may include weight loss, elevated temperature, and generalized itching. Once the disease takes hold, there is a progressive weakening, increasing anemia, and breathlessness. Treatment primarily involves radiotherapy, but there is ongoing development of a series of drugs that seem promising in controlling the disease. It is hoped that these drugs will eventually provide a cure or at least a higher degree of relief. This condition is also referred to as lymphadenoma.