Histones

Proteins rich in arginine and lysine that occur mainly in the cell nucleus and are concerned with the regulation of DNA.


Proteins rich in basic amino acids (e.g., lysine) found complexed with chromosomes of all eucaryotic cells except sperm where the DNA is specifically complexed with another group of basic proteins, the protamines.


Conserved DNA-binding proteins that protect the DNA from free-radical attack.


A simple protein that combines with a nucleic acid to form a nucleoprotein.


One of the five kinds of proteins that are part of chromatin in eukaryotic cells. Their positive charge attracts the negatively charged DNA that is folded around them into units called nucleosomes. Histones also regulate some of the further folding of DNA in chromosomes about to undergo mitosis.


 


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