Is a disease characterized by hemolytic anemia, acute renal failure (uremia) and a low platelet count.
Hemolytic urenmic syndrome (HUS) is a systemic disease marked by renal failure, hemolytic anemia, thrombocytopenia (platelet deficiency), coagulation defects, and variable neurological signs. This disorder is most common in children. It frequently occurs after a gastrointestinal (enteric) infection, often one caused by a strain of specific E. coli bacteria (Escherichia coli 0157:H7). It has also been associated with other enteric infections, including shigella and salmonella, and with some non-enteric infections.
A rare kidney disorder with onset usually in infancy that presents with renal failure, destruction of red blood cells, and platelet deficiency; treatment includes dialysis and conservative treatment with good prognosis for infants and children, but less optimistic outcomes for adults.
A serious disease that involves the destruction of red blood cells, damage to the walls of the blood vessels, and failure of the kidneys. The disease is most likely to occur in children between the ages of 1 and 10 after a serious stomach and intestinal infection. The cause of the infection is often Escherichia coli [E. coli), a bacterium found in contaminated meat, dairy products, and fruit juice. Hemolytic-uremic syndrome occurs only rarely in adults.
An acute condition consisting of microangiopathic hemolytic anemia, thrombocytopenia, and acute nephropathy. Escherichia coli 0157:H7 is a causative agent that may be acquired from eating contaminated raw or rare hamburger or other meats. Children are most often affected. Onset may initially involve gastroenteritis and diarrhea or an upper respiratory tract infection. Hallmarks of the acute phase are a purpuric rash, irritability, and lethargy. Findings include oliguria, splenomegaly, mild jaundice, seizures (in some patients), hepatomegaly, pulmonary edema, and renal failure. The acute phase may last from 1 to 2 weeks in mild cases and much longer in severe cases.
A life-threatening complication of E. coli infections distinguished by renal failure and the lysis of red blood cells.