Any of a group of inherited disorders characterized by an alteration in the normal structure of hemoglobin. Types of hemoglobinopathies include sickle-cell disease and thalassemia.
Inherited disorders involving abnormal hemoglobin molecules. Abnormal hemoglobin is generally less efficient than normal hemoglobin at carrying oxygen to the cells of the body. People with hemoglobinopathies may have mild to moderate anemia and occasional attacks of pain. The most common types of hemoglobinopathy are hemoglobin C disease, which involves the production of abnormal hemoglobin but may not require treatment; hemoglobin S-C disease, which produces mild to moderate anemia, occasional attacks of acute pain, and slightly shorter than normal life spans; hemoglobin E disease, which occurs chiefly in people of Southeast Asian ancestry; and sickle cell anemia.
Any of a group of inherited diseases, including thalassemia and sickle-cell disease, in which there is an abnormality in the production of hemoglobin.
Any one of a group of genetic diseases caused by or associated with the presence of one of several forms of abnormal hemoglobin in the blood.