Grey baby syndrome is an uncommon but potentially life-threatening condition that primarily affects newborns, especially premature babies. It is caused by the antibiotic drug chloramphenicol, which is typically not prescribed for newborns but can be transmitted to the baby through the mother’s bloodstream. Newborns lack the ability to efficiently process or eliminate the drug, leading to dangerously high levels in their bodies. As a result, the affected infant experiences coldness and develops greyish skin due to circulatory collapse.
Early detection of the condition and prompt discontinuation of the drug can lead to full recovery in the infant. Therefore, it is essential to avoid administering chloramphenicol during late pregnancy and while breastfeeding.