Graves’ disease

The name given to the most common form of hyperthyroidism. Patients often have exophthalmos, a goiter, and sometimes raised red patches on the legs, known as pretibial myxedema.


Same as exophthalmic goitre [Described 1835. After Robert James Graves (1796-1853), Irish physician at the Meath Hospital, Dublin, Ireland, where he was responsible for introducing clinical ward work for medical students.]


An autoimmune disease in which the body’s immune system attacks the body’s own thyroid gland by manufacturing antibodies which resemble molecules of thyroid stimulating hormone (TSH). TSH is a hormone that “stimulates” the thyroid gland to increase the metabolic rate of the body. Thus, when the TSH-like antibodies attach themselves to the thyroid gland, the gland mistakes the antibodies for TSH molecules. The thyroid gland causes the body’s metabolism to “go into overdrive”; causing fast heartbeat, agitation, sleeplessness, etc. Grave’s disease is also thought to sometimes cause erratic or violent behavior.


A disease characterized by hyperplasia of the thyroid gland, excessive secretion of its hormones, and increased metabolic rate.


A form of hyperthyroidism caused by excessive thyroid hormone production, resulting in enlargement of the thyroid gland and exophthalmos.


An autoimmune disease that affects the thyroid gland, skin, and eyes. Graves disease may also be referred to as diffuse toxic goiter. It is rarely life threatening and can affect men or women of any age, but is most common in women between 20 and 60 years of age.


A distinct type of hyperthyroidism caused by an autoimmune destruction of the thyroid gland. It typically increases thyroxine (T4) production, produces enlargement of the thyroid gland, and also may cause ocular findings (proptosis, lid lag, and stare).


Graves’ disease, an autoimmune condition affecting the thyroid gland, manifests as a twofold enlargement of the gland and excessive secretion of thyroid hormone. The disorder is named after Robert James Graves, an Irish physician who first documented a case of this condition in 1835.


Graves’ disease is an autoimmune disorder where the immune system attacks the thyroid gland, the body’s own tissues. It is characterized by a toxic goiter, which refers to an overactive and enlarged thyroid gland. This condition leads to excessive production of thyroid hormones (hyperthyroidism), resulting in thyrotoxicosis. Additionally, individuals with Graves’ disease may experience exophthalmos, which is the protrusion or bulging of the eyeballs.


 


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