Goodpasture’s syndrome

A rare lung disease in which someone coughs up blood, is anaemic, and may have kidney failure [Described 1919. After Ernest William Goodpasture (1886-1960), US pathologist.]


A rare autoimmune disease characterized by inflammation of the glomeruli (the filtering units of the kidneys) and bleeding from the lungs. Goodpasture syndrome is a form of rapidly progressive glomerulonephritis that results in a continuous decrease in kidney function. It is more common in males and tends to affect men in their 20s. There is a genetic predisposition, and the risks for developing the disorder are increased by smoking.


The rare autoimmune illness marked by progressive glomerulonephritis, hemoptysis, and hemosiderosis. Death is usually due to renal failure.


Goodpasture’s syndrome is a rare autoimmune disorder characterized by the immune system attacking its own tissues, leading to inflammation in the glomeruli of the kidneys and the alveoli (tiny air sacs) in the lungs. This condition also results in anemia. It is a serious disease, and without early treatment, it can lead to life-threatening lung bleeding and progressive kidney failure. While it is most common in young men, Goodpasture’s syndrome can develop at any age and also affects women.


Treatment for Goodpasture’s syndrome may involve the use of immunosuppressant drugs and plasmapheresis, a procedure that removes harmful antibodies from the blood plasma. Individuals experiencing severe or recurrent episodes of the disorder may require dialysis, a method for eliminating waste products from the blood, and, in the long run, may need to undergo a kidney transplant.


 


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