A measure of the cellular differentiation of prostate cancers that uses the microscopic appearance of biopsied tissue to determine the tumor grade and stage.
This is a method used to classify prostate cancer cells in order to identify the most suitable treatment and predict the patient’s prognosis.
Multiple tissue samples are collected and each is given a score from 1 to 5. The sum of the lowest and highest scores results in the Gleason’s score, a number ranging from 1 to 10. A low Gleason’s score suggests that the cancer cells closely resemble normal prostate cells, while a high score indicates a significant difference. Generally, the more the cancer cells deviate from normal prostate cells, the more severe the cancer.
Multiple tissue samples are collected and each is given a score from 1 to 5. The sum of the lowest and highest scores results in the Gleason’s score, a number ranging from 1 to 10. A low Gleason’s score suggests that the cancer cells closely resemble normal prostate cells, while a high score indicates a significant difference. Generally, the more the cancer cells deviate from normal prostate cells, the more severe the cancer.
The Gleason’s score is frequently used alongside another measure known as the TNM classification, which outlines the degree to which a cancer has metastasized or spread.