A protein constituent of connective tissue. It is present in skin, ligaments, tendons, and in the aorta. In Marfan’s syndrome, there is reduced content of microfibrils that contain fibrillin.
A protein integral to the composition of the body’s connective tissue, known for its significance. However, in Marfan’s syndrome, there is a genetic mutation in the fibrillin gene, resulting in the production of a faulty protein.