Favism

A type of inherited anaemia caused by an allergy to beans.


A condition that develops after consuming certain species (Vicia fabd) of beans; characterized by fever, headache, abdominal pain, severe anemia, prostration, coma, and sometimes death.


Anemia resulting from eating fava beans or breathing in the plant’s pollen. It occurs in the Mediterranean area (e.g., Italy); victims have an inherited blood abnormality and enzyme deficiency. Symptoms include dizziness, headache, fever, vomiting, and diarrhea. Blood transfusions may be required.


An inherited allergy to a chemical substance found in broad beans; it occurs in parts of the Mediterranean and Iran. Destruction of red blood cells may lead to severe anemia, requiring blood transfusion.


A type of haemolytic anaemia, attacks of which occur within an hour or two of eating broad beans (Vicia fava). It is a hereditary disease due to lack of an essential enzyme called glucose-6- phosphate dehydrogenase, which is necessary for the continued integrity of the red cell. This defect is inherited as a sex-linked dominant trait. Fourteen per cent of African-Americans are affected, as are 60 per cent of Yemenite Jews. The gene is thought to have persisted because it also offers resistance against malaria. These red cells are sensitive not only to fava beans and primaquine but also to sulphonamides, acetanilide, phenacetin, para-aminosalicyclic acid, nitrofurantoin, probenecid and vitamin K analogues, all of which can cause a dangerous reaction.


A hereditary condition common in Sicily and Sardinia resulting from sensitivity to a species of bean, Vida faba. It is marked by fever, acute hemolytic anemia, vomiting, and diarrhea, and may lead to prostration and coma. It is caused by ingestion of the beans or inhalation of the pollen of the plant by persons who have an inherited deficiency of the enzyme glucose-6-phosphate dehydrogenase.


This condition is defined by an extreme reaction to the fava bean, also known as Vicia Faba. If a person with this disorder consumes these beans, a compound within the bean triggers the quick breakdown of red blood cells, resulting in a severe form of anemia.


Favism is a rare condition, mostly seen in certain Mediterranean regions. It is a sex-linked genetic disorder, where affected individuals have a G6PD deficiency. This deficiency represents a flaw in a specific chemical process within their red blood cells that usually aids in protecting the cells from damage.


Children who have a family history of favism can undergo testing for the disorder at a young age. If diagnosed, they must abstain from consuming fava beans and also certain medications, like specific antimalarial and antibiotic drugs, which can produce a similar impact on their red blood cells.


 


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