Reduction in synthesis of enzyme protein in response to some stimulus such as a hormone or the presence of large amounts of the end-product of its activity.
Inhibition of enzyme synthesis caused by the availability of the product of that enzyme. On a molecular level a repressor molecule (which could be, for example, the amino acid arginine) combines with a specific repressor protein that is present in the cell. This repressor molecule/repressor protein complex is then able to bind to a specific region of DNA at the initial end of the gene which is called the operator region. It is in this region where the synthesis of mRNA is initiated. The repressor “roadblock” thus stops the synthesis of mRNA, and therefore the synthesis of the protein is also blocked.
Interference with enzyme synthesis by a metabolic product.