Inflammation of the inner lining of an artery or arteries, often associated with advanced syphilis and causing progressive thickening and blocking of the vessel.
Chronic inflammation of the inner (intimal) portion of the wall of an artery, which most often results from late syphilis. Thickening of the wall produces progressive arterial obstrurtion and symptoms from inadequate blood supply to the affected part (‘ischemia). The arteries to the brain are often involved, giving rise to meningovascular syphilis. Endarteritis of the aorta may obstruct the mouths of the coronary arteries, supplying the heart. Endarteritis of the arteries to the wall of the aorta (the vasa vasorum) contributes to ‘aneurysm formation. The syphilitic infection may be eradicated with penicillin.
Infection or inflammation of the lining of a blood vessel.
Endarteritis refers to the inflammation of the innermost layer, or intimal layer, of an artery wall. This condition most frequently arises due to a bacterial infection, such as syphilis. To treat the underlying infection, antibiotic medications like penicillin are typically employed.
Inflammation of the innermost layer of an artery’s wall, which can lead to significant thickening and subsequent blockage.