End stage renal disease

The stage of kidney disease at which uraemia occurs and dialysis needs to start.


Final phase of kidney disease marked by the inability to filter the body’s blood.


Renal (kidney) disease in which the kidneys no longer function enough to sustain life, a condition known as renal insufficiency. Life may be sustained by kidney transplant in some instances, or by hemodialysis (see dialysis). Specific benefits are available for patients with ESRD under Medicare, which is the primary source for paying for long-term hemodialysis, either in the hospital or in the home.


The stage of chronic renal failure in which the clearance of creatinine has decreased so much that the patient will not long survive without renal replacement therapies (e.g., dialysis or kidney transplantation). This stage of renal failure occurs when the creatinine clearance is about 10% of normal, or the glomerular filtration rate is 5 – 10 ml/min. Renal replacement therapies are required to prevent fatal fluid overload, hyperkalemia, and other uremic complications. In the U.S., approximately 400,000 people are actively treated for ESRD with dialysis or kidney transplantation.


Complete renal failure occurs when the kidneys lose their ability to function properly. Chronic kidney failure is identified as end-stage renal disease (ESRD) when kidney function declines to a mere 5-10% of its original capacity.


 


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