Disorders affecting the two Bartholin glands, located on either side of the vaginal entrance, that secrete lubricating fluid during sexual arousal. The gland openings can become blocked from infection or injury. As a result, a Bartholin cyst may form, usually causing no symptoms. However, if the cyst (a fluid-filled sac) becomes infected and an abscess appears (Bartholin abscess), the woman may feel pain and tenderness just inside the vagina, where there will be a warm, swollen lump. Treatment includes an antibiotic for the infection. If the abscess does not respond to antibiotics, the doctor may lance and drain it. About 1 percent of all cancers of the vulva are carcinomas of the Bartholin glands. A tumor of the Bartholin glands or duct may resemble a benign Bartholin cyst.