An autosomal dominant genetic disorder, known as multiple hamartoma syndrome, manifests as the formation of benign growths in various tissues, such as the skin, mouth, and intestines. The dermal growths often exhibit flat-topped, flesh-colored lesions on the facial region. Simultaneously, numerous polyps have the propensity to develop within the intestinal tract.
Individuals affected by Cowden’s disease face an elevated susceptibility to the emergence of specific cancers, notably thyroid cancer, colorectal cancer, and, in women, breast and ovarian cancer. Although no targeted treatment exists for this condition, individuals diagnosed with Cowden’s disease undergo vigilant monitoring to facilitate the early detection of signs indicative of these malignancies. This proactive approach plays a crucial role in ensuring timely intervention and appropriate medical care.