A toxic reaction to the neurotoxin delivered by the pointed, hollow teeth of the marine animal contained in the cone shell. Intense local pain, swelling, and numbness may last several days. In severe poisoning, muscular incoordination and weakness can progress to respiratory paralysis. Although death can occur, recovery within 24 hr is the usual outcome. There is no specific therapy, but supportive measures including artificial respiration and supplemental oxygen may be needed.