Category: P
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Phosphatidylethanolamine
A phospholipid in membranes; an important component (cephalin) of the brain lipids.
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Phosphatidycholine
A phospholipid commonly known as lecithin.
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Phentolamine
A drug that blocks the action of vasopressin in terms of its stimulatory effect on glycogenolysis. A drug that dilates blood vessels and is used to reduce blood pressure in pheochromocytoma and to treat conditions of poor circulation, such as Raynaud’s disease and chilblains. It is administered by mouth or injection; side-effects include fast heart…
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Phenol or phenyl oxidases
Copper-containing enzymes responsible for the browning of fruit at the cut surface. These enzymes can be inhibited by ascorbic acid or by heating. ‘Alcohol-like’ compounds that have the hydroxyl group bound to a benzene ring. A strong disinfectant used for external use. Disinfectant used to clean wounds and, in various lotions and ointments, to treat…
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Phenformin
A biguanide derivative that serves as an oral hypoglycemic agent useful in managing type 2 diabetes mellitus. A drug that reduces blood sugar levels and is used to treat diabetes. It is administered by mouth; side-effects include a metallic taste in the mouth and digestive upsets.
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Phenanthrene
The basic ring structure of the steroid class of compounds. A coal tar derivative that is carcinogenic.
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Peroxisomal fatty acid oxidation
Peroxisomal oxidation in the kidney and liver is an important aspect of drug metabolism. The peroxisomes are a class of subcellular organelles that are important in protection against oxygen toxicity. They have a high level of catalase activity. The peroxisomal fatty acid oxidation pathway differs in three important ways from the mitochondrial pathway. First, the…
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Peroxidation
Oxidation to the point of forming peroxides.
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Patulin
A mycotoxin produced by Penicillium urticae, Penicillium patulum, Penicillium expansum, 12 other species of Penicillium, Aspergillus, and Byssochlamys nivea. It is a wide-spectrum toxicant that is poisonous to mammals, plants, and many lower forms of life. Patulin is stable under conditions required for fruit juice production and preservation. In experimental animals, it has been shown…
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Passive diffusion
A process for the passage of solutes across a membrane that does not involve a carrier or energy.