Category: C

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It is used in the treatment of lymphomas, leukemias, etc. Its side effect, alopecia, has been made use of in defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. A…

Protein kinases that control cell cycle progression in all eukaryotes and require physical association with cyclins to achieve full enzymatic activity. Cyclin-dependent kinases are regulated by phosphorylation and dephosphorylation events. A family of enzymes involved in regulation of the cell cycle. They serve as targets for pharmacological manipulation of this cycle, particularly during the unregulated…

A 33-kD protein identical to adenovirus E1A-associated protein p60. Cyclin A regulates p33cdk2 and p34cdc2, and is necessary for progression through the S phase of the cell cycle.  

Molecule that regulates the cell cycle. A member of a family of proteins that participate in regulating the stages of the cell cycle and whose concentrations change dramatically over the course of the cell cycle.  

Cyanogen bromide (CNBr). A compound used in molecular biology to digest some proteins and as a coupling reagent for phosphoroamidate or pyrophosphate internucleotide bonds in DNA duplexes.  

An extremely toxic class of compounds that can be lethal on inhaling of ingesting in minute quantities. A poison which kills very rapidly when drunk or inhaled. A metabolic poison. It blocks the transport of reducing equivalents from complex III to com¬ plex IV of the respiratory chain in the mitochondria and blocks complex IV…

Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have…

Signals for an action; that specific portion of a perceptual field or pattern of stimuli to which a subject has learned to respond. A specialized form of communication to instigate action. A signal to class participants that might indicate a transition, provide information on safety or form, offer motivation, share feedback, involve imagery, or encourage…

A genus of coccidian parasites of the family Cryptosporidiidae, found in the intestinal epithelium of many vertebrates including humans. A parasite which contaminates drinking water supplies, causing intestinal infection. A microscopic parasite that lives in the intestines of humans and animals and causes cryptosporidiosis. Cryptosporidium is carried in animals without symptoms, particularly in cattle, deer,…

Infection with a fungus of the species Cryptococcus neoformans. A fungal infectious disease often found in the lungs of AIDS patients. It characteristically spreads to the meninges and may also spread to the kidneys and skin. It is due to the fungus Cryptococcus neoformans. An infection mainly affecting the brain or neryous system, caused by…