The production of a carcinoma, carcinogenic.
The process of forming a carcinoma in tissue.
The process of developing cancer.
The origin or development of cancer in previously healthy cells. Carcinogenesis is a multistep process, beginning with a series of changes in the genetic material (DNA) of a single cell. Cells are routinely exposed to substances that can alter their genes, but usually, natural processes of cell repair prevent such alterations. However, when the cell is unable to prevent alterations, its DNA can be permanently changed. When the cell reproduces itself, the new changes in the DNA are reproduced, too. In this way, a single cancer cell can give rise to a family of cells that are not controlled by normal cell repair processes. Unregulated, the new cells will divide rapidly and eventually invade surrounding tissues to form a tumor. Eventually, new cells may break off and move to distant parts of the body, where they can form colonies of cancer cells, called metastases.
Carcinogenesis is the means or method whereby the changes responsible for the induction of cancer are brought about.
The transformation of normal cells into cancer cells, often as a result of chemical, viral, or radioactive damage to genes.
Cancer arises from the transformation of normal cells due to the impact of carcinogens, which are factors capable of causing cancer. The process involves the development of abnormal cellular growth and behavior, leading to the formation of a malignant tumor.
Carcinogens are thought to induce changes in the DNA of cells, specifically in oncogenes, which are responsible for regulating cell growth and division. These genetic alterations prompt affected cells to divide at an abnormal rate, passing on the modified genetic information to their descendant cells. Consequently, a group of cells emerges that evades the normal growth constraints imposed by the body.
The development of carcinoma.