Bone that is abnormally fragile, as in osteogenesis imperfecta.
Fragile bones, prone to fracturing, are a characteristic feature of various conditions. They commonly manifest in individuals with osteoporosis, as well as those who are on corticosteroid medications, experience immobility, or have specific hormonal disorders. In cases of osteomalacia, the bones exhibit a softness that contributes to deformities and an increased susceptibility to fractures. Osteogenesis imperfecta, an inherited disorder, is a rare cause of brittle bones and frequent fractures, often diagnosed during infancy.