A drug that has actions and side effects similar to those of ‘atropine. Taken by mouth, it is used mainly to reduce muscle spasm in parkinsonism.
One of the antimuscarinic group of drugs used to treat parkinsonism. Acting by correcting the relative central cholinergic excess resulting from dopamine deficiency, the drug has a moderate effect, reducing tremor and rigidity but with little action on bradykinesia. It has a synergistic effect when used with levodopa and is useful in reducing sialorrhoea. Valuable in treating cases of Parkinsonian side-effects occurring with certain other drugs. Tardive dyskinesia is not improved and may be made worse.