A collection of fetal malformations associated with multiple fibrous strands of amnion that appear to develop or entangle fetal parts in utero. This leads to structural malformations and deformations and disruption of function. Defects associated with this condition include limb defects and amputations; abnormal dermal ridge patterns; simian creases; clubbed feet; craniofacial defects, including cleft lip and palate; and visceral defects such as gastroschisis and omphalocele. Failure to understand the cause of this condition can lead to misdiagnosis and inappropriate family and genetic counseling.