Agglutination

The clumping of antigens with antibodies or of the red blood cells from one type of blood with the red blood cells of another type.


A clumping together of cells.


The act of coming together or sticking to one another to form a clump, as of bacteria cells in the presence of serum, or blood cells when blood of different of serum, or blood cells when blood of different types is mixed.


A test to identify if a women is pregnant.


In vitro antigen – antibody reaction evidenced by the visible clumping of cells or micro-organisms (the antigen) in the presence of specific antibody contained in serum. Electrolyte (e.g., NaCl) must be present, and temperature and pH optima observed. The cell aggregates thus formed slowly collect as sediment at the bottom of the tube. The strength of the antibody may be deduced from a survey of serial serum dilutions similarly treated.


Clumping together of antigen-carrying cells or microorganisms as a result of their interaction with specific antibodies.


The clumping together of cells as a result of interaction with specific antibodies called agglutinins; agglutinins are used in blood tests that determine the blood type—such as A, B, AB, and O—and Rh factor (positive or negative); derived from a Latin word meaning “glue together”.


A process in which cells suspended in fluid clump together and become visible to the naked eye.


The sticking together, by serum antibodies called agglutinins, of such microscopic antigenic particles as red blood cells or bacteria so that they form visible clumps. Any substance that stimulates the body to produce an agglutinin is called an agglutinogen. Agglutination is a specific reaction; in the laboratory, sera containing different known agglutinins provide an invaluable means of identifying unknown bacteria. When blood of different groups is mixed, agglutination occurs because serum contains natural antibodies (isoagglutinins) that attack red cells of a foreign group, whether previously encountered or not. This is not the same process as occurs in ‘blood coagulation.


A type of antigen-antibody reaction in which a solid cell or particle coated with antigens drops out of solution when it is exposed to a previously soluble antibody. The particles involved commonly include red blood cells, bacteria, and inert carriers such as latex. Agglutination also refers to laboratory tests used to detect specific antigens or antibodies in disease states. When agglutination involves red blood cells, it is called hemagglutination.


The aggregation of red blood cells or bacteria, triggered by particular substances known as agglutinins and agglutinogens.


 


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