A steroid which helps the body produce urine, used in the treatment of oedema and hypertension.
Apotassium-sparing diuretic that is an antihypertensive drug.
Antihypertensive that blocks the action of aldosterone on the renal tubules. Adverse effects include headache, gastrointestinal upset, and hyperkalemia.
A diuretic drug used in combination with other medications to treat high blood pressure and swelling due to liver cirrhosis or congestive heart failure. Spironolactone (Aldactone) is a potassium-sparing diuretic that helps to reduce the amount of the water in the body by acting on the kidneys to increase the flow of urine. This helps lower blood pressure. Unlike other diuretics, spironolactone does not take potassium from the body. Spironolactone is also sometimes prescribed to treat people who have inadequate levels of potassium. It is also used to treat congestive heart failure and excess hair growth in women taking anabolic steroids.
A synthetic corticosteroid that inhibits the activity of the hormone aldosterone and is used to treat heart failure, high blood pressure, and fluid retention (edema). It is administered by mouth; side-effects may include headache, stomach upsets, and drowsiness.
One of the group of substances known as spirolactones. These are steroids similar to aldosterone in structure which competitively act as inhibitors of it; they can thus antagonize the action of aldosterone in the renal tubules. As there is evidence that there is an increased output of aldosterone in oedematous conditions such as congestive heart failure, which accentuates the oedema spironolactone is used, along with other diuretics.
Spironolactone is a type of diuretic medication that conserves potassium and is utilized to manage heart failure and ascites, which is the accumulation of fluid in the abdominal peritoneal cavity. Possible side effects include digestive discomfort, fatigue, skin rashes, sexual dysfunction, and menstrual irregularities. Elevated doses can lead to abnormal breast enlargement, known as gynecomastia, in men.