A disease causing enlargement of the lymph nodes, where small nodules or granulomas form in certain tissues, especially in the lungs or liver and other parts of the body.
Disease of unknown etiology characterized by tumor-like lesions that affect any tissue or organ of the body.
Chronic disease of unknown cause characterized by the formation of nodules in the lungs, liver, lymph glands, and salivary glands. A relationship with tuberculosis is suspected, but has never been proven.
Fibrous invasion by granulomatous tissue in the lungs, skin, lymph nodes, spleen, and parotid glands.
A chronic, multisystem, autoimmune disorder that can affect many body systems, but most commonly involves the lungs or lymph nodes. Sarcoidosis is characterized by the appearance in affected tissues of small, round lumps of dead tissue. These lumps, called granulomas, usually heal and disappear on their own, even without medical treatment. When the granulomas do not resolve, the affected tissues remain inflamed, and scarring develops. The disease is caused by an immune system disorder that occurs for no known reason.
A chronic disorder of unknown cause in which the lymph nodes in many parts of the body are enlarged and small fleshy nodules develop in the lungs, liver, and spleen. The skin, nervous system, and the eyes and salivary glands are also commonly affected, and the condition has features similar to ‘tuberculosis. Recovery is complete with minimal after-effects in two-thirds of all cases.
An uncommon chronic inflammatory disease of unknown origin which can affect many organs, particularly the skin, eyes and lungs. It can first appear as erythema nodosum with lymph-gland enlargement within the chest. In the eyes it causes uveitis. Biopsy of affected tissue allows diagnosis, which is confirmed by a kveim test. Often sarcoidosis is self-limiting, but in severe cases oral corticosteroids may be needed.
A chronic multisystem disease of unknown etiology, characterized by noncaseating (hard) granulomas and lymphocytic alveolitis. Sarcoidosis occurs most often in the southeastern U.S., is 10 times more common in blacks than whites, and is more common in women than men.
The enigmatic ailment, of which the etiology remains obscure, manifests as the development of nodules within the skeletal framework, integumentary system, lymphatic clusters, and pulmonary organs.
An uncommon ailment with an uncertain origin, characterized by widespread inflammation of tissues throughout the body, particularly affecting the lymph nodes, lungs, skin, eyes, and liver. This condition primarily manifests in young adults.
Not all cases exhibit symptoms, but when present, they often encompass fever, widespread discomfort, painful joints, and ocular issues like conjunctivitis and uveitis (painful, bloodshot eyes). Additionally, sarcoidosis can lead to lymph node enlargement, breathing difficulties, erythema nodosum (purple swellings on the legs), a purplish facial rash, and areas of numbness. Potential complications associated with sarcoidosis comprise hypercalcemia (elevated blood calcium levels), which could harm the kidneys, as well as pulmonary fibrosis (lung tissue scarring).
Treatment isn’t universally necessary. The majority of individuals experience complete recovery within a span of two years, whether or not treatment is administered. However, a subset of individuals might develop a persistent, chronic variation of the condition. Corticosteroids are prescribed to address continuous fever or erythema nodosum, prevent blindness in affected eyes, and lower the likelihood of enduring lung impairment.
The cause of this disease is uncertain, and while some consider it to be a reaction to the poison of the tuberculosis germ, others regard it as an allergy disease. It is characterized by granulomatous lesions, principally affecting lymph glands, skin, lungs, and bones, especially in the distal parts of the extremities, but they may arise in any tissue of the body. Sarcoidosis may occur in relationship with leprosy and syphilis, or with the entrance into the body of foreign substances such as silica particles or beryllium. Most patients are middle aged adults, women being affected more frequently than men. When the lungs are affected they exhibit on the x-ray photograph a diffuse, mottled appearance. An appearance similar to this is also seen in the lungs of some hairdressers who have inhaled shellac hair sprays over a long period. This last aspect of the disease has been subject to an investigation by the British Medical Research Council who found only one case out of 506 hairdressers investigated and recommended further research. In the United States, 14 cases were discovered and given the name of thesaurosis. It was believed the cause was breathing air heavily impregnated with insoluble hair spray. The lesions may heal spontaneously or steadily progress and cause increasing disability. Occasionally tuberculosis develops and the sarcoid lesions disappear, while in other cases the patient becomes dangerously ill due to the destruction of the bone marrow by sarcoid infiltration. Also called Boeck ‘s sarcoid, Besnier-Boeck disease, Besnier-Boeck-Schaumann disease, lupus pernio of Besnier, lymphogranulomatosis of Schaumann, benign lymphogranulomatosis.