Is an agent that can cause one of two types of structural changes, breaks in chromosomes that result in the gain, loss, or rearrangements of chromosomal segments. Adj. clastogenic.
Any agent that can damage a chromosome. Examples of clastogens include chemotherapeutic agents (e.g., cyclophosphamide or nitrogen mustard), and many forms of electromagnetic radiation (e.g., ultraviolet light or x-rays).