A reversion of differentiation in cells and is characteristic of malignant neoplasms (tumours).
Loss of structural differentiation, as seen in malignant neoplasms.
Failure of the body cells to function normally, cancer.
The loss of a cell’s typical characteristics, caused by cancer.
Medical term for a cell that has become less differentiated and more “primitive” in form, describing a cell that is malignant, as in cancer. Malignant brain tumors may be described as anaplastic.
Regression of fully developed cells into a more primitive (embryonic) form, occurring in some tumors.
A term applied to cancerous cells that revert to a less developed state in arrangement and structure, a loss of differentiation among cells.
A loss of normal cell characteristics or differentiation, which may be to such a degree that it is impossible to define the origin of the cells. Anaplasia is typical of malignant tumors.
The state in which a body cell loses its distinctive characters and takes on a more primitive form; it occurs, for example, in cancer, when cells proliferate rapidly.
Loss of cellular differentiation and function characteristic of most malignancies.
The transformation of certain advanced cells in an organ or tissue back to a more primitive state, coupled with an abnormal rate of multiplication, as observed in cancerous growths.