Granular cast

A cast composed of cells filled with protein and fatty granules.


A cellular cast derived from a kidney tubule. In certain kidney diseases, notably acute glomerulonephritis, abnormal collections of renal tubular cells are shed from the kidney, often as a cast of the tubule. The casts can be observed on microscopic examination of the centrifuged deposit of a specimen of urine. Their presence in the urine indicates continued activity of the disease.


A coarse or fine granule, short and plump, sometimes yellowish, similar to a hyaline cast, and soluble in acetic acid. It is seen in inflammatory and degenerative nephropathies.


 


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