Felty’s syndrome

A condition, associated with rheumatoid arthritis, in which the spleen is enlarged and the number of white blood cells increases [Described 1924. After Augustus Roi Felty (1895—1963), physician at Hartford Hospital, Connecticut, USA.]


An autoimmune condition characterized by the co-occurrence of neutropenia, rheumatoid arthritis, and an enlarged spleen.


Felty’s syndrome is a condition marked by an unusually large spleen and a diminished white blood cell count. While it can be found in certain individuals with rheumatoid arthritis, its precise origin remains unclear.


The symptoms of Felty’s syndrome can include a general feeling of discomfort, tiredness, decreased appetite, weight loss, anemia, joint swelling and stiffness, along with recurrent infections. Indicators of the condition may involve a swollen spleen and occasionally, enlarged lymph nodes.


The treatment approach for Felty’s syndrome aligns with that for rheumatoid arthritis. In certain situations, a splenectomy, which is a surgical procedure to remove the spleen, might be necessary.


 


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