Erythema nodosum

An inflammatory disease where red swellings appear on the front of the legs.


Tender, reddened nodules on the shins, legs, and occasionally other body areas, often accompanied by fever, muscle and joint pain, and malaise; it occurs in certain diseases, as a drug reaction, and in certain allergic reactions.


An inflammatory skin condition that is characterized by tender, red bumps or swellings under the skin, most often on the shins. Although its exact cause remains unknown, half of all cases are associated with infection with Coccidioides, Mycoplasma, Streptococcus, or Yersinia organisms and diseases such as hepatitis B and tuberculosis. It may also occur as a reaction to drugs such as oral contraceptives or sulfonamides. Some cases have been linked with ulcerative colitis, leukemia, and sarcoidosis.


Erythema nodosum is a condition defined by tender, reddish-purple swellings typically appearing on the legs. It is often linked with another concurrent illness.


The primary cause of erythema nodosum is typically a streptococcal throat infection. Nevertheless, this condition can also be associated with other diseases, especially tuberculosis and sarcoidosis, and may arise as a reaction to certain medications, notably sulphonamide drugs, penicillin, and salicylate drugs. In some cases, there may be no discernible cause.


The swellings associated with this condition can vary in size, from 1 to 10 cm in diameter, and are often shiny and tender. They most frequently appear on the fronts of the shins and thighs, and less commonly, on the arms. Accompanying symptoms usually include joint and muscle pains, as well as fever.


Effective treatment of the underlying condition typically resolves the swellings. Bed rest, pain-relieving drugs (analgesics), and in some cases, corticosteroid drugs may also be required. The condition generally improves within approximately a month.


A toxic erythema that leads to the formation of lumpy swellings, typically on the shins. It is commonly attributed to an allergic response triggered by either medication or pathogenic toxins. In children, a significant proportion of cases are linked to tuberculosis.


 


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