Futile cycle

An enzyme-catalyzed set of cyclic reactions that results in release of thermal energy (heat) through the hydrolysis of ATP (adenosine triphosphate). The hydrolysis of ATP is normally coupled to other cycles and reactions in which the energy released is metabolically used. However, futile cycles would appear to waste the energy of ATP as heat—except when one is shivering to keep warm. The production of heat by shivering is an example of the flitile cycle.


 


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