A variety of serum proteins synthesised in increased (or sometimes decreased) amounts in response to trauma and infection, so confounding their use as indices of nutritional status.
Blood proteins produced in the liver that function in the innate immune response. APPs are important in the response to infection and inflammation.
Any of the plasma proteins whose concentration increases or decreases by at least 25% during inflammation. Acute-phase proteins include C-reactive protein, severed complement and coagulation factors, transport proteins, amyloid, and antiprotease enzymes. They help mediate both positive and negative effects of acute and chronic inflammation, including chemotaxis, phagocytosis, protection against oxygen radicals, and tissue repair. In clinical medicine, the erythrocyte sedimentation rate or serum Creactive protein level sometimes is used as a marker of increased amounts of acute-phase proteins.